Cisplatin-Induced Hypomagnesemia and Renal Toxicity: Clinical Implications

Cisplatin-Induced Hypomagnesemia and Renal Toxicity: Clinical Implications
  • Dr. Alberto Carlos Reino — Nephrologist, Nefron SAS, Medellín, Colombia; Honorary Professor, Universidad de Antioquia, Colombia

Nephrology · Oncology

Cisplatin commonly causes hypomagnesemia by damaging renal tubules and increasing urinary magnesium loss. This deficiency may persist for months after treatment, making regular magnesium monitoring important during therapy and follow-up. Low magnesium levels may also increase susceptibility to cisplatin-related kidney injury by promoting oxidative stress and cellular damage.